Job Url: https://wellfound.com/jobs/3796268-senior-software-engineer-net

Job Description: 
Sema4
Actively Hiring
Sema4 is a predictive & personalized health company
B2B
Public Stage
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Senior Software Engineer, .NET
$165k – $175k
|
Remote (
Remote
)
|6 years of exp
|Full Time
Posted: yesterday• Recruiter recently active
Hires remotely in
Remote
Remote Work Policy
Remote only

Company Location
New York City • 
Stamford
Visa Sponsorship
Not Available

Relocation
Allowed
Skills
C#
SQL Server
MSMQ
Azure
.NET Framework
Docker
Data Modeling
Troubleshooting
AWS
react
Kubernetes
OCI
Vue
Angular
GCP
Event-Driven Architectures
System Performance Metrics
Cloud-Native Microservices
About the job
Summary

As a public and profitable company, we have ambitious plans to scale and enhance our products and services. We’re looking for Senior Software Engineers who can design and deliver high-quality solutions, collaborate effectively across teams, and contribute to meaningful improvements in our platform. Senior engineers at GeneDx focus on owning significant components, contributing to architectural discussions, and delivering reliable, well-tested software.

Job Responsibilities

As a Senior Software Engineer, you'll work on advancing our technology platform and building software products that make a meaningful impact. You will contribute to medium- to large-scale technical efforts, mentor junior engineers, collaborate with cross-functional partners, and deliver robust, scalable solutions aligned with our business objectives.

Day to day tasks may include:

Dive into unfamiliar code to troubleshoot or add a new feature
Participate in feature development of larger projects
Technically lead smaller projects
Participate in Support tasks, including off-hours and weekend on-call rotations.
Propose technical designs, considering standard patterns, tradeoffs, and maintainability
Provide thorough and meaningful code reviews
Work with legacy as well as novel code bases
Prototype, develop, and debug new features
Implement and maintain DevOps cloud patterns
People Manager

No
Education, Experience, and Skills

Proficiency in at least 3 software languages, with a demonstrated ability to quickly learn new ones as needed.

6+ years of software engineering experience, including significant experience in:

.NET Framework and .NET (Core/6+), C#

SQL Server (schema design, performance tuning, migration strategies)

Message queues, ideally MSMQ in production

Demonstrated experience in modernizing legacy applications into cloud‑native microservices and event-driven architectures.

Strong understanding of troubleshooting and maintenance of systems running on a Windows platform

Ability to understand system performance metrics and translate them into actionable improvement tasks

3+ Experience with front-end applications using modern frameworks (React highly desired, but Vue, or Angular are acceptable).

Experience with data modeling using multiple database and storage types.

5+ years experience designing and deploying resilient and scalable large scale and distributed services in the cloud using Docker and Kubernetes (e.g. AWS, GCP, Azure, OCI).

Applied knowledge of multiple architectural paradigms.

Bonus points for:

Prior healthcare / health tech experience, or experience in other regulated industries, particularly with data privacy and compliance requirements.

Bonus points for:

Prior healthcare / health tech experience, or experience in other regulated industries, particularly with data privacy and compliance requirements
Certificates, Licenses, Registrations

None
Physical Demands

This is a sedentary role requiring prolonged periods of sitting while working at a computer. Physical demands include:

Sitting for extended periods (up to 8 hours per day)
Repetitive use of hands and fingers for typing and mouse operation
Visual acuity for reading computer screens and documents
Ability to communicate effectively via phone and video calls
Occasional lifting of up to 10 pounds (office supplies, equipment)
Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions of this position.

Work Environment

This is a fully remote position. The employee will work from a home office or other suitable remote location with reliable high-speed internet access. Work is performed in a climate-controlled environment using standard office equipment including computer, phone, and video conferencing tools. Your standard work schedule and hours will be established in collaboration with your leader and may be adjusted to align with evolving business needs.
Acknowledgements

The above job description is not intended to be an all-inclusive list of duties and standards of the position. Incumbents will follow any other instructions, and perform any other related duties, as assigned by their supervisor.

Pay Transparency, Budgeted Range

$165,000—$175,000 USD